What you have shown are not complete demand loop, supply loops, etc. as described in the EPlus I/O manual and examples.
One boiler tank to supply all the demand is one plant loop. Look up the water heater tank object to see how the branches should be connected. The tank can be gas or electric heated, or puchased hot water. This is the supply side of the tank, which may have a pump.
The domestic main supply is connected to the tank use side loop which may have a pump, which is used as a control valve for domestic water intake.
DHW and radiant panels are all demand loop branches one one heater tank loop.
Bypass branch should be provided so that tank water can be circulated (pump) to maintain the temperature to the tank setpoint value, when there is no demand.
Draw a complete diagram with splitter and mixer and all the branches, and the domestic main water supply and the DWH water tempering valve, you will then have a better idea of the system. There is such a diagram in the I/O Ref. Manual.
Without looking at your IDF, I have no idea how you are simulating your system.
Attachment not found: d:\eudora\attach\Scheme2.jpg